Estudio biodirigido de solanum nigrum y coriaria ruscifolia con actividad antimicrobiana frente a staphylococcus aureus aislados de mastitis bovina
No Thumbnail Available
Date
2025
Journal Title
Journal ISSN
Volume Title
Publisher
PUCE - Ibarra
Abstract
El presente estudio biodirigido de Solanum nigrum y Coriaria ruscifolia, tiene como objetivo principal evaluar la actividad antimicrobiana de extractos de dos plantas medicinales de la región de Imbabura, Ecuador, estas plantas son conocidas como Solanum nigrum (hierba mora) y Coriaria ruscifolia (shashi), contra la bacteria Staphylococcus aureus, causante de la mastitis bovina, debido a que la mastitis constituye una de las enfermedades más prevalentes en el ganado bovino, generando importantes pérdidas económicas para los productores y afectando negativamente el bienestar animal. En este estudio, se propone una estrategia biodirigida para el desarrollo de un tratamiento alternativo contra la mastitis bovina, utilizando extractos de Solanum nigrum y Coriaria ruscifolia. Estas plantas han sido tradicionalmente empleadas en la medicina popular para el tratamiento de diversas afecciones, incluyendo infecciones bacterianas. La investigación se basa en la obtención de extractos concentrados de ambas plantas, mediante procesos estandarizados, para luego evaluar su actividad antimicrobiana contra Staphylococcus aureus. Para ello, se empleará una metodología de diluciones seriadas y pruebas de susceptibilidad microbiana. Los resultados de este estudio proporcionaran evidencia científica sobre el potencial terapéutico de Solanum nigrum y Coriaria ruscifolia en el tratamiento de la mastitis bovina. De esta manera, se podría contribuir al desarrollo de alternativas naturales y sostenibles para el control de esta enfermedad, beneficiando tanto a la salud animal como a la economía del sector ganadero.
The main objective of the present biodirected study of Solanum Nigrum and Coriaria Ruscifolia is to evaluate the antimicrobial activity of extracts of two medicinal plants from the Imbabura region, Ecuador, these plants are known as Solanum nigrum (nightshade) and Coriaria ruscifolia (shashi). , against the bacteria Staphylococcus aureus, which causes bovine mastitis, because mastitis is one of the most prevalent diseases in cattle, generating significant economic losses for producers and negatively affecting animal welfare. In this study, a biodirected strategy is proposed for the development of an alternative treatment against bovine mastitis, using extracts of Solanum nigrum and Coriaria ruscifolia. These plants have traditionally been used in popular medicine to treat various conditions, including bacterial infections. The research is based on obtaining concentrated extracts of both plants, through standardized processes, to then evaluate their antimicrobial activity against Staphylococcus aureus. To do this, a methodology of serial dilutions and microbial susceptibility tests will be used. The results of this study will provide scientific evidence on the therapeutic potential of Solanum nigrum and Coriaria ruscifolia in the treatment of bovine mastitis. In this way, we could contribute to the development of natural and sustainable alternatives for the control of this disease, benefiting both animal health and the economy of the livestock sector.
The main objective of the present biodirected study of Solanum Nigrum and Coriaria Ruscifolia is to evaluate the antimicrobial activity of extracts of two medicinal plants from the Imbabura region, Ecuador, these plants are known as Solanum nigrum (nightshade) and Coriaria ruscifolia (shashi). , against the bacteria Staphylococcus aureus, which causes bovine mastitis, because mastitis is one of the most prevalent diseases in cattle, generating significant economic losses for producers and negatively affecting animal welfare. In this study, a biodirected strategy is proposed for the development of an alternative treatment against bovine mastitis, using extracts of Solanum nigrum and Coriaria ruscifolia. These plants have traditionally been used in popular medicine to treat various conditions, including bacterial infections. The research is based on obtaining concentrated extracts of both plants, through standardized processes, to then evaluate their antimicrobial activity against Staphylococcus aureus. To do this, a methodology of serial dilutions and microbial susceptibility tests will be used. The results of this study will provide scientific evidence on the therapeutic potential of Solanum nigrum and Coriaria ruscifolia in the treatment of bovine mastitis. In this way, we could contribute to the development of natural and sustainable alternatives for the control of this disease, benefiting both animal health and the economy of the livestock sector.
Description
Keywords
Solanum nigrum, Coriaria ruscifolia, Actividad antimicrobiana, Sthapylococcus aureus