Cipriani Ávila, IsabelJara Negrete, Eliza Nuit2023-11-042023-11-042021-072673-4117https://doi.org/10.3390/eng2030020https://repositorio.puce.edu.ec/handle/123456789/6150https://www.mdpi.com/2673-4117/2/3/20Among emerging pollutants, endocrine disruptors such as estradiol are of most concern. Conventional water treatment technologies are not capable of removing this compound from water. This study aims to assess a method that combines physicochemical and biological strategies to eliminate estradio leven when there are other compounds present in the water matrix. Na-montmorillonite, Ca-montmorillonite and zeolite were used to remove estradiol in a medium with sulfamethoxazole, triclosan, and nicotine using a Plackett–Burman experimental design; each treatment was followed by biological filtration with Daphnia magna. Results showed between 40 to 92% estradiol adsorption in clays; no other compounds present in the mixture were adsorbed. The most significant factors for estradiol adsorption were the presence of nicotine and triclosan which favored the adsorption, the use of Ca-montmorillonite, Zeolite, and time did not favor the adsorption of estradiol. After the physicochemical treatment, Daphnia magna was able to remove between 0–93% of the remaining estradiol. The combination of adsorption and biological filtration in optimal conditions allowed the removal of 98% of the initial estradiol concentration.enOpenAccessAguas residuales-TratamientoArcillaAdsorbentesContaminantes emergentesAguas residuales-TratamientoArcillaAdsorbentesContaminantes emergentes