Epidemiology of Candidemia in Latin America: A Laboratory-Based Survey.

Simple item page
dc.careerMedicinaes
dc.category.authorauxiliaryen_US
dc.contributor.authorZurita Salinas, LucĂ­a Jeannete
dc.contributor.correspondingNucci, Marcio
dc.countryEcuadores
dc.date.accessioned2023-11-04T21:36:04Z
dc.date.available2023-11-04T21:36:04Z
dc.date.issued2013
dc.dedication.authorTPes
dc.description.abstractBackground: The epidemiology of candidemia varies depending on the geographic region. Little is known about the epidemiology of candidemia in Latin America. Methods: We conducted a 24-month laboratory-based survey of candidemia in 20 centers of seven Latin American countries. Incidence rates were calculated and the epidemiology of candidemia was characterized. Results: Among 672 episodes of candidemia, 297 (44.2%) occurred in children (23.7% younger than 1 year), 36.2% in adults between 19 and 60 years old and 19.6% in elderly patients. The overall incidence was 1.18 cases per 1,000 admissions, and varied across countries, with the highest incidence in Colombia and the lowest in Chile. Candida albicans (37.6%), C. parapsilosis (26.5%) and C. tropicalis (17.6%) were the leading agents, with great variability in species distribution in the different countries. Most isolates were highly susceptible to fluconazole, voriconazole, amphotericin B and anidulafungin. Fluconazole was the most frequent agent used as primary treatment (65.8%), and the overall 30-day survival was 59.3%. Conclusions: This first large epidemiologic study of candidemia in Latin America showed a high incidence of candidemia, high percentage of children, typical species distribution, with C. albicans, C. parapsilosis and C. tropicalis accounting for the majority of episodes, and low resistance rates.en_US
dc.facultyMedicinaes
dc.id.author1703079119
dc.id.type1
dc.identifier.doi10.1371/journal.pone.0059373
dc.identifier.issn19326203
dc.identifier.urihttps://repositorio.puce.edu.ec/handle/123456789/5485
dc.identifier.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059373
dc.indexed.databaseOtheres
dc.language.isoen
dc.list.authorsNucci, M., Queiroz, F., Alvarado, T., Tiraboschi, I.N., Cortes, J., Zurita, J., Guzman, M., Santolaya, M.E., Thompson, L., Sifuentes, J., Echevarria, J.
dc.magazine.pageRange1-7
dc.magazine.titlePLoS ONEen_US
dc.magazine.volumeChapter8 (3)
dc.rightsClosedAccessen
dc.statepublisheden_US
dc.titleEpidemiology of Candidemia in Latin America: A Laboratory-Based Survey.en_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Epidemiology of Candidemia in Latin America.PDF
Size:
191.77 KB
Format:
Adobe Portable Document Format
Download
Collections
ArtĂ­culos en revistas cientĂ­ficas indexadas (Journals)