A genome-wide survey of genetic instability by transposition in Drosophila hybrids.

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dc.careerCiencias Biológicases
dc.category.authoraddeden_US
dc.contributor.authorVela Peralta, Doris Jimena
dc.contributor.correspondingGarcía Guerreiro, María Pilar
dc.countryEcuadores
dc.date.accessioned2023-11-04T21:30:19Z
dc.date.available2023-11-04T21:30:19Z
dc.date.issued2014
dc.dedication.authorTCes
dc.description.abstractHybridization between species is a genomic instability factor involved in increasing mutation rate and new chromosomal rearrangements. Evidence of a relationship between interspecific hybridization and transposable element mobilization has been reported in different organisms, but most studies are usually performed with particular TEs and do not discuss the real effect of hybridization on the whole genome. We have therefore studied whole genome instability of Drosophila interspecific hybrids, looking for the presence of new AFLP markers in hybrids. A high percentage (27–90%) of the instability markers detected corresponds to TEs belonging to classes I and II. Moreover, three transposable elements (Osvaldo, Helena and Galileo) representative of different families, showed an overall increase of transposition rate in hybrids compared to parental species. This research confirms the hypothesis that hybridization induces genomic instability by transposition bursts and suggests that genomic stress by transposition could contribute to a relaxation of mechanisms controlling TEs in the Drosophila genome.en_US
dc.facultyCiencias Exactas y Naturaleses
dc.id.author1712651197
dc.id.type1
dc.identifier.doi10.1371/journal.pone.0088992
dc.identifier.issn1932-6203
dc.identifier.urihttps://repositorio.puce.edu.ec/handle/123456789/4408
dc.identifier.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088992
dc.indexed.databaseScimago Journal Rankes
dc.language.isoen
dc.list.authorsVela, D., Fontdevila, A., Vieira, C., García, M.P.
dc.magazine.pageRange1-12
dc.magazine.titlePlos Oneen_US
dc.magazine.volumeChapter9 (2)
dc.rightsClosedAccessen
dc.statepublisheden_US
dc.subjectGenetices
dc.subjectNetworkses
dc.subjectTransposablees
dc.subjectElementses
dc.subjectInvertebratees
dc.subjectGenomicses
dc.subjectDrosophilaes
dc.subjectMelanogasteres
dc.subjectGenetic
dc.subjectNetworks
dc.subjectTransposable
dc.subjectElements
dc.subjectInvertebrate
dc.subjectGenomics
dc.subjectDrosophila
dc.subjectMelanogaster
dc.titleA genome-wide survey of genetic instability by transposition in Drosophila hybrids.en_US
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