Barreras multinivel para la investigación clínica y nutricional en América Latina un análisis comparativo socioeconómico

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dc.contributor.authorAngamarca Iguago , Jaime Wladimir
dc.contributor.authorFrias Toral , Evelyn Paola
dc.contributor.authorCalvo Higuera , Isabel
dc.contributor.authorCarriel Mancilla , Jorge Alejandro
dc.contributor.authorContreras Guillermo , Franco
dc.contributor.authorNúñez , Raquel
dc.contributor.authorLarreategui Arosemena , Rosa Ginella
dc.contributor.authorMaza Moscoso, Claudia
dc.contributor.authorRestrepo , Javier
dc.contributor.authorCagua Ordoñez , Jaen
dc.contributor.authorSimancas Racines , Alison
dc.contributor.authorReytor González , Claudia
dc.contributor.authorSimancas Racines, Daniel Alejandro
dc.contributor.correspondingAngamarca Iguago , Jaime Wladimir
dc.date.accessioned2026-07-10T15:12:08Z
dc.date.available2026-07-10T15:12:08Z
dc.date.issued2026
dc.date.issued31/12/2025
dc.description.abstractIntroduction: Clinical and nutritional research in Latin America faces significant challenges that limit scientific development and evidence-based healthcare. Understanding these barriers is essential for developing effective strategies to enhance research capacity in the region. This study aimed to identify multilevel barriers to clinical and nutritional research in Latin America and compare them between countries of different socioeconomic levels. Methods: A cross-sectional study was conducted with 327 healthcare professionals involved in clinical and nutritional research across Latin America. Data collection occurred via an online survey in which participants rated the importance of 16 potential barriers on a 3-point Likert scale. Analysis included descriptive statistics, chi-square tests to compare barriers between upper middle and lower-middle-income countries, logistic regression to identify predictors of research participation, and k-means cluster analysis to identify researcher profiles. Results: Funding (84.4%), research materials (71.6%), and time constraints (70.9%) emerged as the most significant barriers across all countries. Three barriers showed statistically significant differences between income levels: participant commitment (73.6% vs. 42.6%, p < 0.001), frequent appointments (56.6% vs. 37.8%, p = 0.02), and language barriers (39.6% vs. 22.9%, p = 0.02), all of which were higher in lower-middle-income countries. Logistic regression identified the importance of research materials (OR = 0.36, p = 0.002) and telemedicine (OR = 1.74, p = 0.044) as significant predictors of research participation. Cluster analysis revealed three distinct researcher profiles based on barrier perception patterns. Conclusion: Multilevel barriers to research in Latin America are dominated by universal resource constraints (funding, materials, time), with lower-middle income countries facing additional challenges in participant engagement and study logistics. The relative homogeneity of most barriers across income groups suggests that regional and institutional factors may be more influential than national income levels. These findings provide a foundation for developing targeted strategies to strengthen research capacity and infrastructure across Latin America.
dc.id.author1003319868
dc.id.author0917337487
dc.id.author0915868830
dc.id.author0503001000
dc.id.author1719015636
dc.id.author0502274095
dc.identifier.citation"Frias-Toral E, Angamarca-Iguago J, Calvo Higuera I, Carriel-Mancilla J, Contreras G, Franco-Nuñez R, Larreategui Arosemena R,Maza Moscoso C, Restrepo J, Cagua-Ordoñez J, Simancas-Racines A, Reytor-González C and Simancas-Racines D (2025) Multilevel barriers to clinical and nutritional research in Latin America: a socioeconomic comparative analysis.Front. Nutr. 12:1599344.doi: 10.3389/fnut.2025.1599344"
dc.identifier.doihttps://doi.org/10.3389/fnut.2025.1599344
dc.identifier.issn2296861X
dc.identifier.urihttps://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1599344/full
dc.identifier.urihttps://repositorio.puce.edu.ec/handle/123456789/49321
dc.indexed.database2296861X
dc.language.isoen
dc.magazine.pageRange1-16
dc.magazine.titleCódigo Científico Revista de Investigación
dc.magazine.volumeChapterV12
dc.statePublished
dc.subjectClinical research barriers
dc.subjectGlobal health equity
dc.subjectHealth research capacity
dc.subjectKnowledge partnership
dc.subjectLatin America
dc.subjectNutrition science
dc.subjectResearch inequality
dc.subjectScientific infrastructure
dc.titleBarreras multinivel para la investigación clínica y nutricional en América Latina un análisis comparativo socioeconómico
dc.title.alternativeMultilevel barriers to Clinical and nutritional research in Latin América: a socioeconomic comparative analysis
dc.typeArtículo científico
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