Antibacterial and antifungal activity of organic and peptidic extracts of ecuadorian endophytic fungi

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dc.careerEscuela de Ciencias Biológicases
dc.category.authorprincipalen_US
dc.contributor.authorNarváez Trujillo, Elizabeth Alexandra
dc.contributor.authorPortero Pico, Carolina Elizabeth
dc.contributor.correspondingNarváez Trujillo, Elizabeth Alexandra
dc.countryEcuadores
dc.date.accessioned2023-11-04T21:39:13Z
dc.date.available2023-11-04T21:39:13Z
dc.date.issued2021-05
dc.dedication.authorTCes
dc.description.abstractAntibacterial and antifungal activities of 32 organic and 14 peptidic extracts obtained from twelve endophytic fungi of the Collection of Endophytes Quito-Catolica were tested against the pathogenic bacteria Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Escherichia coli and Salmonella enteritidis, and against the fungal oomycete Pythium ultimum. It was observed that the extracts of Marasmiellus candidus (CEQCA-O1113), Xylaria laevis (CEQCA-O1399), Fusarium solani (CEQCA-O1393), Diaporthe helianthi (CEQCA-O1394) and Xylaria sp. (CEQCA-O1400) partially or totally inhibited the microorganisms tested. The extracts CEQCA-O1399.P1 and CEQCA-O1113.D1 showed fungistatic and fungicidal effects against P. ultimum, respectively. Six extracts strongly inhibited S. aureus, and E. coli was strongly inhibited by the extract CEQCA-O1113.E2. Based on a bioassay-guided approach, the extracts with strong bioactivity in the antibacterial assays by an agar diffusion method were also tested by a disk diffusion method, and the minimal inhibitory concentrations were determined by a microdilution assay. The most bioactive extract, CEQCA-O1113.D1, was also purified by high performance liquid chromatography. The extract recovered its initial bioactivity against S. aureus in two fractions after the purification. Overall, the results of this study highlight the potential of the fungal endophytes as producers of bioactive compounds.en_US
dc.facultyCiencias Exactas y Naturaleses
dc.id.author1000620672
dc.id.author1716265309
dc.id.type1
dc.identifier.doi10.4236/aim.2021.115020
dc.identifier.issn2165-3402
dc.identifier.urihttps://repositorio.puce.edu.ec/handle/123456789/5734
dc.identifier.urihttps://www.scirp.org/journal/paperinformation.aspx?paperid=109305
dc.indexed.databaseOtheres
dc.language.isoen
dc.list.authorsVeloz, E. , Portero, C. y Narvaez-Trujillo, A.
dc.magazine.pageRange266-282
dc.magazine.titleAdvances in Microbiologyen_US
dc.magazine.volumeChapter11
dc.rightsOpenAccessen
dc.statepublisheden_US
dc.subjectCompuestos Bioactivoses
dc.subjectInhibición del Crecimientoes
dc.subjectBacterias Patógenases
dc.subjectCompuestos Bioactivos
dc.subjectInhibición del Crecimiento
dc.subjectBacterias Patógenas
dc.titleAntibacterial and antifungal activity of organic and peptidic extracts of ecuadorian endophytic fungien_US
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